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糖尿病主要是由胰岛素绝对或相对不足,或靶细胞对胰岛素敏感性降低,引起的以糖代谢紊乱为主的慢性综合性疾病。1型糖尿病(T1DM)主要表现为β细胞免疫性进行性破坏、衰竭,2型糖尿病(T2DM)的发生是外周胰岛素抵抗和β细胞功能缺陷共同作用的结果。全球约有3.66亿的糖尿病患者,约占总人口的8.3%,至2030将增至5.52亿,约占总人口的9.9%,其中T2DM约占95%~([1])。进
Diabetes is mainly due to the absolute or relative lack of insulin, or target cells to reduce the sensitivity of insulin, caused by glucose metabolism disorder-based chronic diseases. Type 1 diabetes mellitus (T1DM) manifests itself as progressive destruction of beta cell immunity, failure, and the development of type 2 diabetes mellitus (T2DM) as a result of a combination of peripheral insulin resistance and beta cell dysfunction. There are about 366 million diabetic patients in the world, accounting for about 8.3% of the total population. By 2030, the number will increase to 552 million, accounting for about 9.9% of the total population, of which about 95% of T2DM (~ 1). Enter