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本文观察了17例慢性乙型肝炎及15例正常人外周血共1663个淋巴细胞染色体。用 G显带技术证明了肝炎患者染色体及某些组号染色体的畸变率较正常人明显增高。同时观察到 e 抗原阳性、肝功能明显受损的患者,其染色体畸变率较高,且可出现标记染色体。探讨了染色体畸变与慢性肝炎的发病机理及先天性愚型的关系。
In this paper, a total of 1663 lymphocytes chromosomes were observed in 17 cases of chronic hepatitis B and 15 cases of normal human peripheral blood. Using G-banding technology to prove the chromosome aberration of hepatitis patients and some group of chromosomes was significantly higher than normal. At the same time observed e antigen positive, significantly impaired liver function in patients with higher rates of chromosome aberrations, and markers can appear chromosomes. The relationship between chromosomal aberration and the pathogenesis of chronic hepatitis and idiopathic stupidity were explored.