Parallel Synthesis ofα-Acylamino Amide Library by Ugi four-component Condensation Reaction

• 作 者: XuPing LinWenwei ZhangTing HuX
• 机 构: DepartmentofMedicinalChemistry,DeparimentofPharmacy.YichangMedicalSchool
• 出 处: 中国药学：英文版
• 发表日期: 2001年1期
• 关键词: 多组份反应 异腈 Ugi反应 缩合条件 化合物 反应条件

Ugi-4CC(four-component condensation) reaction is one of isonitrile-based MCR's(multicomponent reactions), which is started with an amine, an aldehyde, a carboxylic acid and an isocyanide, after full use of the specialty of isonitrile and be used to bu