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目的:肠易激综合征(IBS)是一类以腹痛及排便习惯改 变为特征的胃肠功能性疾病,内脏痛觉过敏可能是其重要的病理生理基础之一。本研究的目的在于应用血氧水平依赖性功能磁共振成像(BOLD—fMRI)技术,探讨直肠气囊扩张刺激下大脑内脏痛觉中枢的兴奋情况,并比较IBS患者在不同容量刺激下兴奋区分布、范围及强度与正常人群的差异性。方
Objective: Irritable bowel syndrome (IBS) is a type of gastrointestinal dysfunction characterized by changes in abdominal pain and bowel habits. Visceral hyperalgesia may be one of the important pathophysiological bases. The purpose of this study was to explore the excitability of the visceral central nervous system of the brain under stimulation of rectal balloon with BOLD-fMRI technique and to compare the distribution of excitement in IBS patients under different volume stimuli. And intensity and the normal population differences. square