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Magnius和Espmark(1971)在HB_sAg阳性血清中发现一组新的抗原抗体系统,并命名为“e”。以后的作者指出了e抗原抗体系统仅和HB_sAg系统同时存在,并认为e抗原的存在与肝功能损害、肝组织学异常及预后相关,而e抗体的意义则相反。近年来也有认为这种相关不是绝对的。我们于1977年4月至1977年11月对乙型肝炎患者及乙型肝炎相关抗原(下称HB_sAg)携带者480例、HB_sAg阴性肝炎患者150例及健康者66人作了e抗原抗体(下称eAg-eAb)的测定,并对25份血清标准作了电子显微镜观察,现初步报告如下。
Magnius and Espmark (1971) found a new set of antigen-antibody systems in HBsAg-positive sera and named them “e”. Later authors pointed out that the e antigen-antibody system exists only with the HB_sAg system, and that the presence of e antigen is associated with liver dysfunction, abnormal liver histology and prognosis, while the meaning of e antibody is the opposite. In recent years, some people think that this correlation is not absolute. From April 1977 to November 1977, we performed e antigenic antibody tests on 480 patients with hepatitis B and carriers of hepatitis B virus (HBsAg), 150 patients with HBsAg negative hepatitis and 66 healthy individuals Called eAg-eAb) determination, and 25 serum standards made by electron microscopy, the initial report is as follows.