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为了评估检测IgM特异性抗-HCV在诊断和监测丙型肝炎患者上可能的作用,作者发展了一种简单的改良抗-HCV免疫检测法,以检测IgM抗-HCV。对14例急性、97例慢性非甲非乙型肝炎患者作系列的血清IgG和IgM抗-HCV检测;对20例健康供血者、20例急性甲型肝炎患者和20例急性、30例慢性乙型肝炎患者作血清IgM抗-HCV检测。结果表明,非甲非乙型肝炎患者中,急性病例93％(13/14),慢性病例91％(88/97)检出IgG抗-HCV。101例IgG抗-HCV阳性的患者中,58例(57％)IgM抗-HCV阳性。健康供血者、急性甲型肝炎患
To assess the possible role of IgM-specific anti-HCV in the diagnosis and monitoring of patients with hepatitis C, the authors developed a simple modified anti-HCV immunoassay to detect IgM anti-HCV. Serum IgG and IgM anti-HCV were detected in 14 acute and 97 chronic non-A non-B hepatitis patients. Twenty healthy donors, 20 acute hepatitis A patients and 20 acute, 30 chronic B Hepatitis patients for serum IgM anti-HCV test. The results showed that 93% (13/14) of acute non-hepatitis B patients and 91% (88/97) of chronic patients were detected IgG anti-HCV. Of the 101 IgG anti-HCV positive patients, 58 (57%) were IgM anti-HCV positive. Healthy blood donor, suffering from acute hepatitis