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近年来,中枢神经系统白血病(CNSL)发生率呈增高趋势,CNSL的早期诊断与治疗是延和白血病患者生存期、提高治愈率的关键之一,但中枢神经系统受累程度与临床表现有时并不一致,赖以确诊的脑脊液生化及细胞学检查易出现假阳性或假阴性干扰。我们观察了急性白血病有CNSL组和无CNSL组的脑脊液铁蛋白含量变化,以探讨其对CNSL早期诊断及疗效观察的价值1 材料和方法
In recent years, the incidence of central nervous system leukemia (CNSL) showed an increasing trend. The early diagnosis and treatment of CNSL is one of the keys to prolong the survival and improve the cure rate of patients with leukemia. However, the degree of central nervous system involvement is sometimes inconsistent with clinical manifestations , Depending on the diagnosis of cerebrospinal fluid biochemical and cytology prone to false positive or false negative interference. We observed changes in cerebrospinal fluid ferritin levels in patients with acute leukemia with and without CNSL to investigate their value in the early diagnosis and efficacy of CNSL.1 Materials and Methods