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目的探讨前哨淋巴结(sentinel lymph node,SLN)标记在腹腔镜结肠癌术中应用的可行性及其临床意义。方法20例腹腔镜结肠癌手术与同期20例开腹结肠癌手术SLN标记相比较。结果两组SLN检出率、SLN及非前哨淋巴结检出数、SLN平均显色时间及SLN检测准确率、特异性、假阴性率、阳性及阴性预测值比较差异无统计学意义(P>0.05)。结论腹腔镜结肠癌术中行SLN标记是可行的,对SLN进行详细的组织病理学检查能准确地预测区域淋巴结转移情况、提高肿瘤分期的准确性。
Objective To investigate the feasibility and clinical significance of the use of sentinel lymph node (SLN) markers in laparoscopic colon cancer surgery. Methods Twenty cases of laparoscopic colon cancer surgery were compared with those of 20 cases of open colon cancer surgery during the same period. Results There was no significant difference in SLN detection rate, SLN and SLN count, SLN average colorimetric time and SLN detection accuracy, specificity, false negative rate, positive and negative predictive value (P> 0.05 ). Conclusion SLN marking is feasible in laparoscopic colon cancer surgery. Detailed histopathological examination of SLN can accurately predict the regional lymph node metastasis and improve the accuracy of tumor staging.