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目的:探讨应用高渗盐溶液抢救重型颅脑损伤并失血性休克的优越性和可行性。方法:对42例重型颅脑损伤并失血性休克患者早期一次性静脉滴注7.5%高渗氯化钠溶液400mL,之后应用等渗盐水或低分子右旋糖酐维持。结果:42例重型颅脑损伤并失血性休克患者,除3例心脏大血管损伤、3例脑干损伤患者应用高渗盐溶液治疗无效死亡外,其余患者疗效满意,均恢复相对平稳生命体征,无不良反应发生。结论:高渗盐溶液用于重型颅脑损伤并失血性休克患者早期急救,可快速提升血压,改善微循环,减少液体用量,降低颅内压,是一种安全、有效的救治方法。
Objective: To investigate the superiority and feasibility of using hypertonic saline solution to rescue severe head injury and hemorrhagic shock. Methods: Forty-two patients with severe craniocerebral injury and hemorrhagic shock were treated with intravenous infusion of 400 mL of 7.5% hypertonic sodium chloride solution in the early stage and then maintained with isotonic saline or low molecular weight dextran. Results: In 42 cases of severe craniocerebral injury and hemorrhagic shock, except for 3 cases of cardiac vessel injury and 3 cases of brain stem injury, hypertonic saline solution was used to treat ineffective death. The rest patients were satisfied with the curative effect and all recovered relatively stable vital signs, No adverse reactions occurred. Conclusion: The hypertonic saline solution is used in the early emergency treatment of patients with severe craniocerebral injury and hemorrhagic shock. It can raise blood pressure rapidly, improve microcirculation, reduce liquid dosage and reduce intracranial pressure. It is a safe and effective treatment method.