An Efficient Cationic Cyclization Approach for the Construction of Labdane Diterpenoid Decalin Ring

• 出 处: Chinese Chemical Letters
• 发表日期: 2005年04期
• 关键词: epoxy isomers cyclization ketone chair cited sequential preliminary herein elsew

An effective approach for the construction of the decalin ring skeleton of labdane diterpenoids was developed based on a key biomimetic cationic polyene cyclization of an epoxy allylsilane precursor. The synthetic approach demonstrated here would be useful in the enantioselective and diastereoselective total synthesis of natural labdane diterpenoids in general.

An effective approach for the construction of the decalin ring skeleton of labdane diterpenoids was developed based on a key biomimetic cationic polyene cyclization of an epoxy allylsilane precursor. The synthetic approach demonstrated that would be useful in the enantioselective and diastereoselective total synthesis of natural labdane diterpenoids in general.