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据目前所知,IUD的局部炎症反应可能损伤受精前的精子或着床前的囊胚,也改变子宫内膜,使内膜不利于接受囊胚,阻止着床或破坏已着床胚胎的发育。由于测定人类绒毛膜促性腺激素(hCG)的技术问题,不是与LH发生交叉反应出现假阳性,就是尿内hCG浓度低,用常规的测定方法包括β-hCG测定法在内亦测不出,而出现假阴性。本研究用免疫放射测量法(IRMA)测定hCG浓度,对此课题进行研究。 IRMA是一种无LH交叉反应,可以在尿内测
To the best of our knowledge, the local inflammatory response of IUD may damage pre-fertilized spermatozoa or pre-implantation blastocysts and also alter the endometrium, rendering the intima unfavorable for receiving blastocysts, preventing implantation or disrupting the development of an implanted embryo . Because of the technical problem of determining human chorionic gonadotropin (hCG), false positives are not caused by cross-reaction with LH, that is, the urinary hCG concentration is low and can not be measured by conventional assay methods including β-hCG assay, False negatives appear. In this study, immunohistochemistry (IRMA) determination of hCG concentration, the subject of research. IRMA is a non-LH cross-reaction that can be measured in urine