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目的观察宁泌泰胶囊联合抗生素治疗湿热下注型急性肾盂肾炎的临床疗效。方法将90例患者随机分为治疗组(60例)和对照组(30例);对照组给予抗生素治疗,治疗组给予宁泌泰胶囊联合抗生素治疗,疗程2周;观察两组临床疗效及症状积分、尿检查结果变化情况。结果治疗组愈显率为83.05%,对照组为66.67%;两组临床疗效比较有显著性差异(P<0.05)。治疗后,两组临床症状积分均显著降低(P<0.001),但组间差异无统计学意义(P>0.05);治疗组中段尿培养细菌转阴率高于对照组(94.28%vs 80.00%,P<0.05);治疗后两组及随访两周时尿红细胞和白细胞均较治疗前减少(P<0.001)。结论宁泌泰胶囊联合抗生素治疗湿热下注型急性肾盂肾炎临床疗效确切。
Objective To observe the clinical effect of Ningbitai Capsule combined with antibiotics in treating acute pyelonephritis with infusion of damp-heat. Methods 90 patients were randomly divided into treatment group (60 cases) and control group (30 cases). The control group was treated with antibiotics. The treatment group was given Ningbitai capsule combined with antibiotics for 2 weeks. The clinical efficacy and symptoms Points, urine test results change. Results The cure rate was 83.05% in the treatment group and 66.67% in the control group. There was significant difference between the two groups in clinical curative effect (P <0.05). After treatment, the clinical symptom scores of both groups were significantly decreased (P <0.001), but there was no significant difference between the two groups (P> 0.05). The negative rate of bacterial culture in the middle of the treatment group was higher than that of the control group (94.28% vs 80.00% , P <0.05). Urine red blood cells and white blood cells decreased after treatment in both groups and two weeks after treatment (P <0.001). Conclusion Ningbitai capsule combined antibiotics in the treatment of acute pyelonephritis clinical effect is accurate.