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非选择性β-肾上腺素能阻滞剂(噻吗心安、左旋心得乐、卡特心安等)在青光眼治疗中已被广泛应用,但付作用较多,特别可引起支气管痉挛,故青光眼合并肺部疾病时应用受到限制。丙烯心安是选择性β-肾上腺素能阻滞剂中最常用药物,不引起支气管痉挛,逐渐受到重视。为此,研究丙烯心安对原发性开角型青光眼患者的眼压、房水动力学、眼血液动力学、视功能及血压和心率的影响,并和噻吗心安的降压效果作比较。选择35例(57眼)眼压中度或高度升高的早期或发展期开角型青光眼患者与观察对象。男8例,女27例。年龄56～80岁(平均66±1岁)。早期24眼、发展期32眼、晚期1眼。4例有支气管哮喘,3例有低血压。治疗前停用一切降眼压药物7～14天。31例(50眼)点0.5％丙烯心安眼液每日二次,每次一滴;4例(7眼)因治疗前眼压太高还加用1％匹罗卡品眼液每日二次。用眼压计(10.0g)测量眼压,《OφT—10》型眼
Non-selective beta-adrenergic blockers (timolol, levodopa, carter, etc.) have been widely used in the treatment of glaucoma, but pay more, in particular, can cause bronchospasm, it is associated with glaucoma lung Disease application is limited. Propranolol is the most commonly used selective β-adrenergic blockers, does not cause bronchospasm, and gradually receive attention. To investigate the effects of propylene-propylene on IOP, aqueous humor, ocular hemodynamics, visual function, blood pressure and heart rate in patients with primary open-angle glaucoma, and to compare the antihypertensive effect of timolol. Thirty-five patients (57 eyes) with early or advanced open-angle glaucoma and moderate or elevated intraocular pressure were selected and observed. 8 males and 27 females. Age 56 to 80 years (mean 66 ± 1 years). 24 eyes in early stage, 32 eyes in advanced stage and 1 late stage. 4 cases of bronchial asthma, 3 cases of hypotension. Before treatment, disable all ocular hypotensive drugs 7 to 14 days. Thirty-one patients (50 eyes) were treated with 0.5% propylene-propylene-acetate eye drops twice daily, and 4 eyes (7 eyes) were treated with 1% pilocarpine twice daily before treatment due to high intraocular pressure . The intraocular pressure was measured using tonometer (10.0 g), “OφT-10” type eye