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脑塞通为吉林省特产研究所制药厂生产的中成药。由红参、黄芩、牛膝、花粉、桃仁、川芎、琥珀、硃砂等21味中药组成。临床上治疗脑栓塞收到较好效果。本文则报告脑塞通的抗血栓作用及其机制。一、对体外直栓形成的影响将30只大鼠等分3组,第2、3组分别按1g/kg,0.5g/kg灌胃脑塞通,第1组给予等体积水,每日2次,连续给药7日,于末次给药后2h,大鼠腹腔注射戊巴比妥钠45mg/kg麻醉,用硅化注射器由腹主动脉取血2ml,迅速置于特制的硅化胶管内,用XSN-R型体外血栓形成仪(江苏无锡县电子仪器二厂制造)旋转10
Naositong is a proprietary Chinese medicine produced by the Pharmaceutical Factory of Jilin Provincial Institute of Special Products. It consists of 21 Chinese herbs, including red ginseng, astragalus, achyranthes, pollen, peach kernel, Chuanxiong, amber and cinnabar. Clinical treatment of cerebral embolism received good results. This article reports the antithrombotic effects and mechanism of Naosaitong. First, the impact on the formation of direct suppository in vitro 30 rats were equally divided into 3 groups, the second group and 3 groups were fed 1g/kg, 0.5g/kg gavage brain plug, group 1 was given an equal volume of water, daily 2 times, continuous administration for 7 days, 2 hours after the last administration, the rat was anesthetized with sodium pentobarbital 45 mg/kg by intraperitoneal injection, 2 ml blood was taken from the abdominal aorta using a siliconized syringe, and quickly placed in a special siliconized hose, XSN-R in vitro thrombosis analyzer (made by Jiangsu Wuxi Electronic Instrument Factory) rotation 10