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头孢三嗪,作为头孢菌素类抗生素,自应用于临床以来,由于该药的抗菌谱广,抗菌力强,在临床抗感染治疗中得到了广泛地应用。又由于该药无严重的副作用及毒性反应,尤其对机体重要脏器无明显的毒性损害,而更适宜于小儿患者及合并肝肾功能不全的患者。 我院近3年来,应用上海先锋药业公司生产的头孢三嗪,治疗伤寒合并肝功能损害的患者,取得了较为理想的治疗效果。现将典型病例报道如下。 1 资料与方法 患者计某,女性4 1/2岁,因持续性发热一厨伴腹痛腹泻而就诊。体格检查,患者呈急性病容,精神萎靡,咽部充血,两肺呼吸音略粗,腹平软无明显压痛,肝脾无明显肿大,神经系统无阳性体征。实验室检查,血白细胞计数7.1×10~9/L,嗜酸性细胞计数0,血肥达氏检验,H 1:640,O 1:640,血培养查到伤寒杆菌。 根据以上情况,患者系伤寒,诊断明确,我院应用上海
Ceftriaxone, as a cephalosporin antibiotic, has been widely used in the clinical anti-infective treatment since it has been widely used in the clinical anti-infective treatment since its antibacterial spectrum is broad and antibacterial is strong since its clinical application. And because the drug has no serious side effects and toxicity, especially on the vital organs of the body without obvious toxicity damage, but more suitable for pediatric patients and patients with liver and kidney dysfunction. Our hospital nearly 3 years, the application of cephalosporin triazine pharmaceutical production company in Shanghai Pioneer, the treatment of typhoid fever patients with liver damage, and achieved a more ideal therapeutic effect. Typical cases are reported below. 1 Materials and Methods Patients, a female, 4 1½ years old, due to persistent fever, a chef with abdominal pain and diarrhea and treatment. Physical examination, the patient was acute disease, apathetic, pharyngeal hyperemia, respiratory sounds slightly coarse lung, abdominal tenderness was no tenderness, liver and spleen no significant enlargement, no positive signs of the nervous system. Laboratory tests, blood leukocyte count 7.1 × 10 ~ 9 / L, eosinophil count 0, blood fat Dahs test, H 1: 640, O 1: 640, blood culture found Salmonella typhi. According to the above situation, patients with typhoid fever, a clear diagnosis, our hospital Shanghai