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目的了解金华市男男性行为人群(MSM)的艾滋病病毒(HIV)抗体阳转及高危行为变化情况。方法采用前瞻性队列研究,招募符合纳入标准的MSM组建队列。纳入队列的MSM每隔3个月进行一次随访调查,并采集血样检测HIV抗体。结果共纳入90名HIV抗体阴性的MSM,队列基线调查艾滋病防治核心知识知晓率为83.3%,队列保持率为78.9%(71/90),比较基线调查和随访到的性行为情况,随着随访次数增加,最近3个月与同性性伴发生安全性行为所占构成比增加;最近3个月与固定同性性伴和临时同性性伴发生性行为时都采取保护措施的比例有明显提高,与异性性伴发生性行为时安全套使用情况无变化。HIV血清抗体阳转率为3.9/100人年。结论参与队列定期随访和检测后,MSM的高危性行为有所下降。由MSM社会组织鼓励动员参加定期随访和检测是值得推广的有效干预措施。
Objective To investigate the positive changes of HIV antibody and high-risk behavior of MSM in Jinhua City. Methods A prospective cohort study was conducted to enlist MSM formation cohorts that met the inclusion criteria. Cohort MSMs were followed up every 3 months and blood samples were collected for the detection of HIV antibodies. Results A total of 90 HIV-negative MSM were included in the cohort. The core knowledge of HIV prevention and treatment was 83.3% in the baseline cohort and 78.9% (71/90) in the cohort. Compared with baseline and follow-up sexual behavior, The number of safe behaviors increased with the number of same-sex sexual partners in the last 3 months. The percentage of protective measures taken in the last 3 months when having sex with both same sex partners and temporary same-sex partners increased significantly, No change in condom use during heterosexual sexual activity. HIV seroconversion rate was 3.9 / 100 person-years. Conclusions After participating in the regular follow-up and testing of the cohort, the high-risk sexual behaviors of MSM decreased. Encouraged by MSM community organizations to mobilize for regular follow-up and testing is an effective intervention worth promoting.