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目的:对黄皮Clausena lansium叶的化学成分进行分离和鉴定。方法:采用正相(硅胶)、反相(ODS)、凝胶柱色谱和高效液相制备方法进行分离纯化,利用波谱数据和理化常数鉴定化合物的结构。结果:从乙醇提取物中分离鉴定了7个化合物,分别为corchoionoside C(1),1′-O-β-D-glucopyranosyl(2R,3S)-3-hydroxynodakenetin(2),槲皮素-3-O-刺槐双糖(3),芦丁(4),槲皮素-3-O-β-D-吡喃葡萄糖-(1→4)-α-L-吡喃鼠李糖苷(5),山柰酚-3-O-α-L-吡喃鼠李糖-(1→2)-[α-L-吡喃鼠李糖-(1→6)]-β-D-吡喃葡萄糖苷(6),山柰酚-3-O-α-L-吡喃鼠李糖-(1→2)-[α-L-吡喃鼠李糖-(1→6)]-β-D-吡喃半乳糖苷(7)。结论:化合物1~7均为首次从该属植物中分离得到。
Objective: To isolate and identify the chemical constituents of Clausena lansium leaves. Methods: The compounds were isolated and purified by normal phase (silica gel), reverse phase (ODS), gel column chromatography and high performance liquid phase preparative methods. Their structures were identified by spectral data and physico-chemical constants. Results: Seven compounds were isolated and identified as corchoionoside C (1), 1’-O- β -D-glucopyranosyl (2R, 3S) -3-hydroxynodakenetin (4), quercetin -3-O-β-D-glucopyranosyl- (1 → 4) -α-L-rhamnopyranoside (5) , Kaempferol-3-O-α-L-rhamnopyranosyl- (1 → 2) - [α-L-rhamnopyranosyl- (1 → 6)] - β-D-glucopyranose Glycosides (6), kaempferol-3-O-α-L-rhamnopyranosyl- (1 → 2) - [α-L-rhamnopyranosyl- (1 → 6)] - - galactopyranoside (7). Conclusion: Compounds 1 ~ 7 were isolated from this genus for the first time.