One-pot-synthesis of novel cinchonine-based phosphites

• 作 者: Qiao Feng Wang Xue Ying Liu Xi
• 机 构: Department of Chemistry
• 出 处: 中国化学快报（英文版）
• 发表日期: 2004年期
• 关键词: Cinchona alkaloids Diols Chiral phosphite Asymmetric reaction Ligand
• 基金项目: We are grateful to the National Natural Science Foundation of China;Natural Science Basic Research Plan in Shaanxi Province of China

Cinchonine was employed as backbone for the synthesis of novel phosphite compounds with diol substituents. These monophosphinites were provided in one pot with the yields ranged from 63% to 75%. Their structures were confirmed by NMR spectroscopy and HRMS.