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肝肺综合征(HPS)是多见于肝硬化患者的一种综合病征,其发病机制复杂且未完全阐明。内皮源性血管物质一氧化氮(NO)和内皮素-1(ET-1)在其发病机制中的作用已成为研究热点。深入了解其发病机制可为HPS的治疗提供新的途径。
Hepatopulmonary syndrome (HPS) is a common syndrome in patients with cirrhosis, its pathogenesis is complex and not fully elucidated. The role of endothelium-derived vascular nitric oxide (NO) and endothelin-1 (ET-1) in their pathogenesis has become a research hotspot. In-depth understanding of its pathogenesis can provide a new way for the treatment of HPS.