Degradation of retinoid X receptor α by TPA through proteasome pathway in gastric cancer cells

• 作 者: Xiao-FengYe SuLiu Qiaowu Xiao-
• 机 构: KeyLaboratoryoftheMinistryofEducationforCellBiologyandTumorCellEngineering
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2003年9期
• 关键词: 胃癌 类维生素A受体X TPA BGC-823细胞
• 基金项目: 国家自然科学基金，福建省自然科学基金

AIM: To investigate and determine the mechanism and signal pathway of tetradecanoylphorbol-1, 3-acetate (TPA) in degradation of RXRα.METHODS: Gastric cancer cell line, BGC-823 was used in the experiments. The expression level of R XRα protein was detected