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应用光镜、电镜观察四例临床已确诊的黑人充血性心肌病尸检心脏改变,特征是心脏显著扩大,心壁稍增厚但松软,肌纤维肥大,间质纤维组织增生,肌原纤维排列紊乱或溶解,Z 带异常,线粒体数量增多,大小不一,线粒体内可见平行致密带状物及基质内致密的包涵物以及其他退行性变,这些病变虽然不是充血性心肌病特有的变化,但与其他一些心脏疾病包括肥厚性心肌病所见病变有所不同,如能结合临床所见,可作出肯定的诊断。在线粒体内见到包涵物及平行致密带状物,作者认为可能是饮酒引起的充血性心肌病的一种较有特征性的形态学改变。
Four cases of clinically diagnosed congestive heart failure of congestive cardiomyopathy were observed by light and electron microscopy. The heart was characterized by a marked enlargement of the heart, a slightly thickening of the heart wall but softness, hypertrophy of the muscle fibers, interstitial fibrosis, disorganized myofibril or Dissolution, Z zone abnormalities, an increase in the number of mitochondria, the size of different, mitochondria visible parallel dense ribbons and stromal dense inclusions and other degenerative changes, although these lesions are not unique changes in congestive cardiomyopathy, but with other Some heart diseases, including hypertrophic cardiomyopathy seen lesions are different, if combined with the clinical findings, can make a positive diagnosis. In the mitochondria to see inclusions and parallel dense ribbon, the authors believe that alcohol consumption may cause congestive cardiomyopathy is a more characteristic morphological changes.