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目的:探讨保留肾脏的输尿管部分切除术治疗原发性输尿管癌的长期疗效。方法:回顾性分析1999年3月~2013年2月行保留肾脏的输尿管部分切除术的31例输尿管癌患者临床资料:12例患者行输尿管膀胱再植术,19例行输尿管端端吻合术。随访14~171个月,观察术后尿路肿瘤复发率、患者总体生存率、肿瘤分期及病理分级方面分层生存率等情况。结果:术后尿路肿瘤复发率为19.35%(6/31);总体5年及10年生存率分别为77.41%、58.64%;低肿瘤分期组5年及10年生存率均为86.67%,高肿瘤分期组5年及10年生存率分别为74.93%和54.29%;低病理分级组5年及10年生存率均为76.00%,高病理分级组5年及10年生存率分别为78.26%和48.83%。结论:在严密随访下,输尿管部分切除术可以有效治疗低分期、低分级输尿管癌。
Objective: To investigate the long-term efficacy of partial ureter resection with renal preservation in the treatment of primary ureteral carcinoma. Methods: The clinical data of 31 patients with ureteral carcinoma who underwent partial ureter excision of the kidneys from March 1999 to February 2013 were retrospectively analyzed. Twelve patients underwent ureteral bladder replantation and 19 underwent ureteral end-to-end anastomosis. The patients were followed up for 14 to 171 months. The postoperative recurrence rate of urinary tract tumor, overall survival rate, tumor staging and histological grade of stratified survival rate were observed. Results: The recurrence rate of postoperative urinary tract tumors was 19.35% (6/31). The 5-year and 10-year overall survival rates were 77.41% and 58.64% respectively. The 5-year and 10-year survival rates were 86.67% The 5-year and 10-year survival rates were 74.93% and 54.29% in the high-grade staging group respectively. The 5-year and 10-year survival rates were 76.00% in the low-grade group and 5 years and 10-year survival rates were 78.26% And 48.83% respectively. Conclusions: Under close follow-up, partial ureterrectomy can effectively treat low-grade, low-grade ureteral carcinoma.