论文部分内容阅读
目的探讨获得性癫癎失语综合征(LKS)的临床特征及治疗反应。方法通过对4例LKS患儿临床表现、EEG特征、治疗效果观察,并通过电话及门诊复诊随访其预后。结果 4例患儿均予丙戊酸钠口服溶液及激素治疗,3~6个月抽搐发作控制,失语明显好转,EEG提示不同程度改善。结论 LKS是一少见的年龄依赖性癫癎综合征,以失语和癫癎发作为主要表现,可伴有行为异常,EEG以颞区为主的癎样放电,睡眠期可泛化全导,抗癫癎药物可控制癫癎发作,但对失语疗效欠佳,早期足量激素治疗对失语疗效明显。该病预后较好。
Objective To investigate the clinical characteristics and therapeutic response of acquired epileptic seizure syndrome (LKS). Methods The clinical manifestations, EEG features and therapeutic effects of 4 children with LKS were observed, and their prognosis was followed up by phone and outpatient referral. Results All the 4 patients were given sodium valproate oral solution and hormone therapy, 3 to 6 months of seizure control, aphasia was significantly improved, EEG prompts to varying degrees of improvement. Conclusion LKS is a rare age-dependent epilepsy syndrome. Aphasia and epileptic seizures are the main manifestations of LKS, which may be associated with behavioral abnormalities. EEG mainly discharges in the temporal region. Epilepsy drugs can control the onset of epilepsy, but the poor efficacy of aphasia, adequate hormone therapy early treatment of aphasia significantly. The prognosis of the disease is better.