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我们就尤消化道出血时使用大剂量肝素对出血速率的影响进行观察,以探讨在消化道出血的血管造影中使用大剂量肝素对出血显示的影响及安全性。 材料和方法 普通成年健康家犬9条,体重8~16 kg用2.5%戊巴比妥钠溶液(1 ml/kg)静脉内麻醉。动物模型制作:全麻下打开腹腔并暴露出部分空肠或回肠肠段,用带硅胶导管(10~15 cm)的3~6号头皮针,在肠系膜上动脉的某一空、回肠动脉及分支穿刺,造成出血后,将出血导管引入肠腔或腹腔内模拟消化道出血,或以切断肠系膜上动脉血管远端之小分支或切开肠壁造成出血。用带刻度的试
We observed the effects of high-dose heparin on the bleeding rate in the case of gastrointestinal hemorrhage to investigate the effect and safety of high-dose heparin on bleeding in angiographically induced gastrointestinal bleeding. Materials and Methods Nine adult healthy dogs, weighing 8-16 kg, were anesthetized intravenously with 2.5% sodium pentobarbital solution (1 ml / kg). Animal model: open the abdominal cavity under general anesthesia and expose part of the jejunum or ileum, with a silicone catheter (10 ~ 15 cm) 3 to 6 scalp needles in the superior mesenteric artery in a void, ileal artery and branch puncture , Resulting in bleeding, the bleeding catheter into the intestine or abdominal cavity to simulate gastrointestinal bleeding, or to cut off the distal superior mesenteric artery of the small branch or cut the intestinal wall bleeding. Use a graduated test