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唇形科香茶菜属(Rabdosia)植物在日本用于治疗胃肠道疾病,中国则用作抗肿瘤和抗炎剂,有几篇关于香茶菜属二萜的化学和生物活性的综述已经发表。本文报道鄂西香茶菜(Rabdosia henryj(Hemsl.)Hara)的一个新二萜—4-表鄂西香茶菜素A,(4-epi-henryine A_1)分离和结构。结构是通过光谱数据确定的,为鄂西香茶菜素A(henryine A)的4-差向异构体。鄂西香茶菜1986年10月采自湖北省陨西县,地上部分用95％乙醇回流,浓缩后的乙醇提取物在乙酸乙酯中研匀,乙酸乙酯层用5％碳酸钠振摇除去有机酸,干燥、蒸发,
Rabdosia plants are used in Japan for the treatment of gastrointestinal diseases, while in China they are used as anti-tumor and anti-inflammatory agents. There have been several reviews of the chemical and biological activities of the diterpenoids of the genus Cassia. Published. This paper reports on the isolation and structure of a new diterpene- 4-epi-henryine A_1 from Rabdosia henryj (Hemsl.) Hara. The structure is determined from the spectral data and is the 4-epimer of henryine A in western Hubei. The western Hubei Xiangcai was collected from Luxi County, Hubei Province in October 1986. The aerial part was refluxed with 95% ethanol. The concentrated ethanol extract was ground in ethyl acetate and the ethyl acetate layer was shaken with 5% sodium carbonate. Organic acids, drying, evaporation,