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本文采用放射免疫测定法对39例喉癌患者和40例健康老年人的血清T3、T4进行测定,以观察喉癌患者甲状腺机能变化。结果是T3前者较后者明显降低,经t检验有极显著差异(P<0.01);T4两者无显差异(P>0.05)。同时表明患者的甲状腺机能与伤口愈合和预防咽瘘有明显关系。因此认为,喉癌患者行手术治疗时,不论是否已行放疗,术前和术后均应检测甲状腺功能,以对术后愈合提供参考。
In this paper, radioimmunoassay of 39 cases of laryngeal cancer patients and 40 healthy elderly serum T3, T4 were measured in order to observe the thyroid function changes in patients with laryngeal cancer. The result was that the former T3 was significantly lower than the latter, with significant difference (P <0.01) by t-test and no significant difference between the two groups (P> 0.05). At the same time shows that the patient’s thyroid function and wound healing and prevention of pharyngeal fistula have a clear relationship. Therefore, laryngeal cancer patients undergoing surgical treatment, whether or not radiation has been performed, preoperative and postoperative thyroid function should be detected in order to provide a reference for postoperative healing.