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目的 :探讨非胰岛素依赖型糖尿病 (2型糖尿病 )患者心血管自主神经功能与 QT离散度 (Q Td)、JT离散度 (JTd)和室性心律失常发生的关系。方法 :2型糖尿病患者 31例 ,按照标准心血管自主神经功能试验的结果分成阳性者及阴性组 ,16例健康人为正常对照组。所有入选人员均测 QTd、JTd及 2 4h Holter心电监测 ,并进行心律失常分析和比较。结果 :2型糖尿病患者心血管自主神经功能异常的发生率为 5 4.8% ,其发生率与病程呈正相关 ,QTd与 JTd显著延长 ,室性心律失常的发生率较高。结论 :QTd和 JTd可作为一项 2型糖尿病自主神经功能异常者发生室性心律失常重要的预测指标
Objective: To investigate the relationship between cardiovascular autonomic nervous function (QT), JTd (JTd) and ventricular arrhythmia in non-insulin dependent diabetes mellitus (type 2 diabetes mellitus). Methods: Twenty-one patients with type 2 diabetes mellitus were divided into positive and negative groups according to the results of standard cardiovascular autonomic nervous function test, and 16 healthy individuals were normal control group. All participants were measured QTd, JTd and 24h Holter ECG monitoring, and arrhythmia analysis and comparison. Results: The incidence of cardiovascular autonomic dysfunction in patients with type 2 diabetes was 54.8%. The incidence was positively correlated with the course of the disease. The QTd and JTd were significantly prolonged and the incidence of ventricular arrhythmia was higher. Conclusion: QTd and JTd can be used as an important predictor of ventricular arrhythmia in patients with type 2 diabetes mellitus with autonomic dysfunction