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目的:分析新疆维、汉两民族老年高血压病患者血尿酸水平差异及与血糖、血脂代谢的相关性。方法:将2014年1月至2014年12月在新疆维吾尔自治区人民医院就诊的1 433例维、汉老年高血压患者根据血尿酸水平分为高血压伴高尿酸组(观察组267例)、高血压正常血尿酸组(对照组1 166例),分析2组间血糖、血脂发生情况及民族差异。结果:汉族老年高血压病患者血尿酸水平高于维吾尔族,差异有统计学意义(P<0.05)。甘油三酯(TG)、高密度脂蛋白(HDL-C)、血肌酐(Scr)、尿素氮(BUN)2组比较,差异有统计学意义(P<0.05),低密度脂蛋白(LDL-C)、总胆固醇(TC)、空腹血糖(FBG)2组比较,差异无统计学意义(P>0.05)。血尿酸水平与TG、CCr、BUN呈显著正相关(P<0.05),与HDL、空腹血糖呈负相关(P<0.05)。结论:血尿酸水平存在民族性差异,监测并干预高血压病患者尿酸水平能有效改善老年人代谢性疾病及心脑血管疾病病情。
OBJECTIVE: To analyze the difference of serum uric acid level and the relationship with blood glucose and blood lipid metabolism in elderly patients with hypertension in Xinjiang Uygur and Han ethnic groups. Methods: From January 2014 to December 2014, 1 433 hypertensive patients with hypertension in the Han and Han Chinese from the People’s Hospital of Xinjiang Uygur Autonomous Region were divided into hyperuricemia group (267 cases) and high uric acid group Blood pressure normal uric acid group (control group, 1 166 cases), analysis of blood glucose, lipid profile and ethnic differences between the two groups. Results: The level of serum uric acid in Han elderly patients with hypertension was higher than Uygur nationality (P <0.05). TG, HDL-C, Scr and BUN in the two groups were significantly different (P <0.05). The levels of LDL- (P> 0.05). There was no significant difference between the two groups (P> 0.05). There was no significant difference between the two groups (C> C), total cholesterol (TC) and fasting blood glucose (FBG) The level of serum uric acid was positively correlated with TG, CCr and BUN (P <0.05), but negatively correlated with HDL and fasting blood glucose (P <0.05). Conclusion: There are ethnic differences in serum uric acid levels. Monitoring and intervention of uric acid levels in hypertensive patients can effectively improve the metabolic diseases and cardiovascular and cerebrovascular diseases in the elderly.