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自体骨髓移植(ABMT)目前应用较多,但主要报道治疗急性白血病、淋巴瘤及某些实体瘤,而其它恶性血液病国内未见报道。我院1992年曾进行2例恶性组织细胞病(恶组)及多发性骨髓瘤(骨髓瘤)的自体骨髓移植治疗,现报告如下。例1女,15岁,学生,1991年6月因高热,乏力,多汗,齿龈出血,鼻衄,苍白入院,经临床及骨髓细胞学诊断方恶组。临床有重度贫血外观,巩膜无黄染,浅表淋巴结不大,胸骨轻叩痛,肝未触及,脾肋下4cm,腹水征(一)。化验:Hb47g/L,WBC1.4×10~9/L,BPC46×10~9/L。骨髓象:有核细胞增生活跃,粒红比13:1,细胞见较多异形网状细池,占9％,异形网状细胞的形态特点:胞体大,外形不规则,浆深
Autologous bone marrow transplantation (ABMT) is currently used more, but the main report of the treatment of acute leukemia, lymphoma and some solid tumors, while other hematological malignancies have not been reported in the country. In our hospital in 1992 had 2 cases of malignant cell disease (evil group) and multiple myeloma (myeloma) autologous bone marrow transplantation, are as follows. Example 1 Female, 15 years old, student, June 1991 Due to fever, fatigue, hyperhidrosis, bleeding gums, epistaxis, pale admission, clinical and bone marrow cytology diagnosed Fangxiao group. Clinical appearance of severe anemia, scleral no yellow dye, superficial lymph nodes, sternal pain, the liver has not touched, spleen ribs 4cm, ascites sign (a). Assay: Hb47g / L, WBC1.4 × 10 ~ 9 / L, BPC46 × 10 ~ 9 / L. Bone marrow: nucleated cell hyperplasia, grainy than 13: 1, cells see more reticular fine pool, accounting for 9%, shaped reticular cells morphological characteristics: large cell body, irregular shape, the depth of the pulp