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目的对小儿手足口病实施干扰素联合炎琥宁治疗的临床效果进行探讨。方法选取84例小儿手足口病患儿随机分成两组,各42例;对照组给予干扰素治疗,观察组给予干扰素联合炎琥宁治疗,比较探讨两组临床治疗效果。结果在治疗总有效率上,观察组为95.24%,明显要比对照组的71.43%高(P<0.05)。从退热时间、疱疹消失时间、口腔溃疡愈合时间3项指标来看,观察组均快于对照组(P<0.05);而观察组的住院时间则显著短于对照组(P<0.05)。结论在临床中,干扰素联合炎琥宁治疗小儿手足口病具备明显的疗效,具备推广及应用的价值。
Objective To investigate the clinical effect of interferon combined with mesylate in children with hand-foot-mouth disease. Methods Eighty-four pediatric HFMD children were randomly divided into two groups (n = 42 in each group). The control group was treated with interferon and the observation group was treated with interferon plus yanhuning. The clinical effects of the two groups were compared. Results The total effective rate in the observation group was 95.24%, significantly higher than 71.43% in the control group (P <0.05). The observation group was faster than the control group (P <0.05), while the observation group’s hospitalization time was significantly shorter than that of the control group (P <0.05), from the three indicators of fever, disappearance of herpes and healing time of oral ulcer. Conclusions In the clinical trial, interferon combined with metronidazole in children with HFMD has obvious curative effect, which has the value of popularization and application.