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目的:对肝硬化合并肝性脑病的临床诊治进行分析和探讨。方法:收集该院120例肝硬化合并肝性脑病患者,然后将120例患者随机分为观察组(60例)和对照组(60例),对对照组的肝硬化合并肝性脑病患者采用冬氨酸、鸟氨酸进行治疗,对观察组的硬化合并肝性脑病患者对对照组治疗的基础上加用乙酰谷酰胺并进行肠道清洗和营养支持治疗,对两组患者的治疗效果分进行比较和分析。结果:经不同方法治疗后,观察组的总有效率、血氨浓度优于对照组,两组之间的差异具有统计学意义(96.67%vs85.00%,30±4vs59±6)(P<0.05)。结论:冬氨酸、鸟氨酸、乙酰谷酰胺联合肠道清洗及营养支持治疗在肝硬化合并肝性脑病中的治疗效果显著,可有效改善患者肝功能,值得临床推广。
Objective: To analyze and discuss the clinical diagnosis and treatment of cirrhosis with hepatic encephalopathy. Methods: A total of 120 patients with cirrhosis and hepatic encephalopathy were collected from the hospital. 120 patients were randomly divided into observation group (60 cases) and control group (60 cases). Patients in control group with cirrhosis and hepatic encephalopathy were treated with winter Ornithine for treatment of patients with sclerosis combined with hepatic encephalopathy observed in the control group on the basis of the treatment plus acetylglutamine and intestinal cleansing and nutritional support for treatment of patients in two groups were divided into comparison and analysis. Results: The total effective rate and blood ammonia concentration of the observation group were better than those of the control group after treatment by different methods. The difference between the two groups was statistically significant (96.67% vs 85.00%, 30 ± 4 vs 59 ± 6) (P < 0.05). CONCLUSION: Aspartic acid, ornithine, acetylglutamine combined with intestinal cleaning and nutritional support therapy have significant therapeutic effect in patients with cirrhosis and hepatic encephalopathy, which can effectively improve the liver function and deserve clinical promotion.