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目的了解ＴＴ病毒（简称ＴＴＶ）在血液透析患者和骨髓移植患者中的感染情况，并评估ＴＴ病毒的致病力。方法回顾性调查３７例血液透析患者和９０例骨髓移植患者的ＴＴＶ感染情况，分析ＴＴＶ感染的致病力。结果ＴＴＶ在３７例血液透析患者中的感染率为１６２２％（６／３７），在９０例骨髓移植患者中的感染率为３３３％（３／９０），经统计学处理，两组感染率比较有显著性差异。６例ＴＴＶ阳性患者中５例有输血史，４例行肾移植术。ＴＴＶ感染与是否存在ＨＢＶ或ＨＣＶ感染无关。未发现ＴＴＶ阳性和ＴＴＶ阴性两组之间肝功能的损害程度存在差异。结论输血或血浆在传播ＴＴＶ感染上有重要意义。ＴＴＶ的致病力较弱。ＴＴＶ是否嗜肝病毒，有待进一步研究。
Objective To investigate the infection of TT virus (referred to as TTV) in hemodialysis patients and bone marrow transplant patients, and to evaluate the virulence of TT virus. Methods Retrospective investigation of 37 cases of hemodialysis patients and 90 cases of bone marrow transplantation in patients with TTV infection, analysis of pathogenicity of TTV infection. Results The infection rate of TTV was 1622% (6/37) in 37 hemodialysis patients and 333% (3/90) in 90 cases of bone marrow transplantation. After statistical analysis, Group infection rates were significantly different. Five of the six TTV positive patients had a history of blood transfusions and four had kidney transplants. TTV infection is not associated with the presence of HBV or HCV infection. There was no difference in the extent of damage to liver function between TTV-positive and TTV-negative groups. Conclusion Blood transfusion or plasma in the transmission of TTV infection is important. TTV virulence is weaker. Whether TTV is hepadnavirus remains to be further studied.