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为探讨提高胃癌患者胃液中肿瘤相关抗原的检出率及早期胃癌检测的敏感性，应用以胃癌单克隆抗体的特异性和聚合酶链反应（ＰＣＲ）的高度敏感性相结合建立的免疫－ＰＣＲ检测胃液中肿瘤相关抗原ＭＧ７Ａｇ。结果胃癌３７例、慢性萎缩性胃炎８例、慢性浅表性胃炎４例及消化性溃疡８例，胃液中ＭＧ７Ａｇ阳性分别为３０例、２例、０例及１例，胃癌患者胃液中ＭＧ７Ａｇ的阳性检出率为８１．１％。结果提示该方法对诊断胃癌有较大的应用价值
To investigate the increase in the detection rate of gastric cancer-associated antigens in gastric cancer patients and the sensitivity of early gastric cancer detection, an immuno-PCR based on the combination of the specificity of monoclonal antibodies against gastric cancer and the high sensitivity of polymerase chain reaction (PCR) was used. Detection of tumor-associated antigen MG7Ag in gastric juice. Results There were 37 cases of gastric cancer, 8 cases of chronic atrophic gastritis, 4 cases of chronic superficial gastritis, and 8 cases of peptic ulcer. The MG7Ag positive in gastric juice was 30 cases, 2 cases, 0 cases and 1 case respectively. The gastric juice contained MG7Ag in gastric cancer patients. The positive detection rate was 81.1%. The results suggest that this method has great application value in the diagnosis of gastric cancer