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目前绒毛膜上皮癌的治疗主要是手术,应用放射治疗和雄激素治疗意见尚不一致,近来较注意用大剂量雌激素。应用大剂量雌激素治疗绒毛膜上皮癌,是由于它能抑制垂体促性腺的机能,这样就能使产生促性腺激素的组织活动性减少。Smith氏认为给与本病患者注射卵泡素后,尿内绒毛膜促性腺素显著减少;在雌激素治疗时尿内绒毛膜促性腺素滴度显著减低。绒毛膜上皮癌患者的雌激素量减少,Hinglais氏等信为绒毛膜上皮癌细胞不产生雌激素,而正常的绒毛膜能产生雌激素。
The current treatment of choriocarcinoma is mainly surgery, the application of radiation and androgen treatment is not the same opinion, the recent pay more attention to high-dose estrogen. The application of high-dose estrogen in the treatment of choriocarcinoma, because it can inhibit the function of the gonadal pituitary gland, so gonadotropin-producing tissue will be able to reduce activity. Smith believes there is a significant reduction in urinary chorionic gonadotropin following the injection of follicle-stimulating hormone in patients with this disease; the urinary chorionic gonadotropin titer is significantly reduced during estrogen therapy. Estrogen levels are reduced in patients with choriocarcinoma. Hinglais et al. Report that estrogen is not produced by choriocarcinoma cells, whereas normal chorion produces estrogen.