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据《全国中草药汇编》所载,卫矛科雷公藤属植物供药用的有雷公藤(Tripterygium wilfordij Hook.f.)、昆明山海棠(Tripterygium hypoglaucum〈Levl.〉Hutch.)与黑蔓即东北雷公藤(Tripterygiumregeli Sprague et Tak.),临床使用以前两种为常见。近年来,雷公藤属植物在治疗类风湿性关节炎、系统性红斑狼疮、硬皮病、皮肌炎、银屑病、肾病综合症、慢性肾炎等多种难治的自身免疫性疾病中取得了显著疗效,临床报道与实验研究与日俱增,十分活跃。有人认为本品首载于《本草纲目拾遗》。实际上,《本草纲目拾遗》所载之“雷公藤”是蓼科蓼属植物扛板归(Polygonum perforliatum L.)。
According to the “National Collection of Chinese Herbs,” Tripterygium wilfordij Hook.f., Tripterygium hypoglaucum (Levl. Hutch.) Tripterygium regeli Sprague et Tak. is common in clinical use. In recent years, Tripterygium has been used to treat various refractory autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, scleroderma, dermatomyositis, psoriasis, nephrotic syndrome, and chronic nephritis. With remarkable results, clinical reports and experimental studies are increasing and are very active. Some people think that this product was first included in the “Supplement to Compendium of Materia Medica”. In fact, the “Hybrid Tripe” contained in the “Supplement to Compendium of Materia Medica” is the Polygonum perforliatum L..