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18例头皮脂溢性皮炎,使用1%联苯(艹 卡)唑酊剂外用治疗,全部取得临床痊愈,12例病原菌培养转阴性。对从头皮屑培养出的糠秕孢子菌6株作了最小抑菌浓度(MIC)测定。联苯苄唑对糠秕孢子菌的MIC为0.25—0.5μg/me,略优于酮康唑和咪康唑。 临床和实验室结果表明:联苯苄唑外用治疗头皮脂溢性皮炎是一种有希望的药物;对糠秕孢子菌是脂溢性皮炎的条件致病菌的学说提供新的支持
18 cases of seborrheic dermatitis, topical treatment with 1% biphenyl (艹 card) azole tincture, all achieved clinical recovery, 12 cases of pathogen culture negative. Six strains of Pityrosporum cultivated from dandruff were tested for their minimum inhibitory concentration (MIC). Bifonazole against Pityrosporum MIC 0.25-0.5μg / me, slightly better than ketoconazole and miconazole. Clinical and laboratory results indicate that topical use of bifonazole is a promising drug for the treatment of seborrheic dermatitis; new support is provided for the doctrine of opportunistic pathogens in which Pityrosporum is seborrheic dermatitis