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目的探讨培土生金化瘀方对改善慢性阻塞性肺病稳定期临床症状、体征及生活质量的临床效果。方法对照组:给予茶碱缓释胶囊、沐舒坦片、沙丁胺醇气雾剂等常规治疗,治疗组在对照组基础上加服用培土生金化瘀方。于服药前及服药第4周分别做各项指标测定,分别比较两组治疗前后及两组间的症状、体征及生活质量变化。结果治疗组与对照组在治疗后相比较,在咳嗽、咳痰、气喘改善上差异有统计学意义(P<0.01);在啰音改善上,差异也有统计学意义(P<0.05)。以上症状、体征的改善情况,治疗组均优于对照组。与治疗组治疗前生活质量得分相比,治疗组治疗后的得分差异有统计学意义(P<0.05),且治疗后生活质量得到改善;治疗组与对照组在治疗后的得分比较,治疗组的改善情优于对照组(P<0.05)。结论培土生金化瘀方在治疗慢性阻塞性肺病稳定期临床症状,体征及生活质量具有一定的改善效果,值得推广。
Objective To investigate the clinical effects of “Peixue Shengjin Huayu Decoction” on improving the clinical symptoms, signs and quality of life in chronic phase of chronic obstructive pulmonary disease (COPD). Methods Control group: given theophylline sustained-release capsules, mucosolvan tablets, salbutamol aerosol and other conventional treatment, the treatment group on the basis of the control group plus take Peibu Sheng Jin Huayu Fang. The indexes were measured before medication and the fourth week of medication respectively. The symptoms, signs and quality of life of the two groups before and after treatment and between the two groups were compared. Results The difference between the treatment group and the control group after treatment was statistically significant (P <0.01) in the improvement of cough, expectoration and asthma. There was also a significant difference in the improvement of rales (P <0.05). The above symptoms and signs of improvement, the treatment group were better than the control group. Compared with the treatment group before treatment quality of life scores, the treatment group after treatment scores were statistically significant (P <0.05), and quality of life improved after treatment; treatment group and control group after treatment scores, the treatment group The improvement was better than the control group (P <0.05). Conclusions Pusushengjinhuayu Recipe has certain improvement effect in the treatment of clinical symptoms, signs and quality of life in the stable stage of chronic obstructive pulmonary disease and is worth promoting.