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应用MTT法检测46例胃癌手术切除标本对8种常用的化疗药物的体外敏感性，探讨此方法作为胃癌术后化疗用药依据的可靠性。结果表明：不同个体胃癌对同种化疗药物的敏感性不同，其中以羟基喜树碱、顺铂等敏感性较高。根据试验结果选择药物行术后化疗，随访1、2年生存率分别为94．7％（36／38）、79．2％（19／24）。结论：提示此药敏试验对胃癌术后辅助化疗方案的选择有指导意义。
MTT assay was used to detect the sensitivity of eight commonly used chemotherapeutic drugs in 46 cases of gastric cancer resected specimens and the reliability of this method as a basis for postoperative chemotherapy of gastric cancer. The results showed that: different individual gastric cancer sensitivity to the same chemotherapy drugs are different, including hydroxycamptothecin, cisplatin and other high sensitivity. According to the results of the trial, the drug was selected for postoperative chemotherapy. The 1-year and 2-year follow-up survival rates were 94.7% (36/38) and 79.2% (19/24), respectively. Conclusion: This drug sensitivity test suggests that the choice of postoperative adjuvant chemotherapy regimen should be instructive.