论文部分内容阅读
研究背景:婴儿痉挛症为婴儿的一种严重癫痫性疾病,死亡率高且难治疗。既往几十年中,激素疗法(促肾上腺皮质激素和去氢氢化可的松)已成为主要的治疗方法,但却很少有证据支持此疗法。据记载,氨己烯酸对此病有效。目的:氨己烯酸与去氢化可的松和替可克肽均可治疗婴儿痉挛症,本文对比分析两类药物的治疗效果。方法:本研究为多中心随机对照试验,在英国150所医院进行,由英国婴儿痉挛研究中心评测结果。以用药第13和14天时痉挛停止作为有效治疗结果指标。最小
Background: Infantile spasms are a serious epileptic condition in infants with high mortality and refractoryness. Hormone therapy (corticotropin and hydrocortisone) has been the dominant treatment for decades, but there is little evidence to support this therapy. According to records, amino acid is effective against this disease. OBJECTIVE: Both hexamidine and hydrocortisone and teicopirin can treat infantile spasms. This article compares and analyzes the therapeutic effects of two drugs. METHODS: This multicenter randomized controlled trial was conducted in 150 UK hospitals and was evaluated by the UK Infantile Spasm Research Center. Stop using spasms on days 13 and 14 as an indication of effective treatment outcome. Min