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采用组织细胞化学直接荧光法测定24例宫颈癌和36例子宫内膜癌的组织细胞中雌激素受体(ER),并以正常宫颈组织和子宫内膜组织做对照。其结果显示:①宫颈癌组织细胞中存在雌激素受体明显高于正常宫颈组织。②宫颈癌组织中,腺癌的受体含量高于鳞癌,但癌组织中ER状况与病理分级、临床期别、月经状况无明显相关。③子宫内膜癌组织细胞中ER平均含量较高。但与正常宫内膜组织细胞中ER含量相比较,则无显著性差异。④在宫体癌分化好的癌组织中,ER高于分化差的癌组织。与病理学分类、临床分期以及月经状况无相关。
Tissue cells of 24 cases of cervical cancer and 36 cases of endometrial carcinoma were assayed for estrogen receptor (ER) by histocytochemical direct fluorescence method. The normal cervical tissues and endometrial tissues were used as controls. The results showed that: ① Cervical cancer cells in estrogen receptor was significantly higher than normal cervical tissue. ② cervical cancer, adenocarcinoma receptor content higher than squamous cell carcinoma, but the ER status in cancer tissue and pathological grade, clinical stage, menstrual status no significant correlation. ③ endometrial cancer cells in the average higher level of ER. However, compared with normal endometrial cells ER content, there was no significant difference. ④ In well differentiated carcinoma of the uterine body, ER is higher than poorly differentiated carcinoma. No correlation with pathological classification, clinical stage and menstrual status.