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目的观察灯盏花注射液对缺血性脑血管病血液流变学及经颅多普勒(TCD)的影响。方法90例缺血性脑血管病患者随机分成2组,45例用灯盏花注射液40ml加入液体250ml中静脉滴注,每日一次,20天为一疗程;45例以复方丹参注射液治疗作对照。观察灯盏花治疗后血液流变学和TCD的改善情况。结果灯盏花能明显降低血浆粘度、红细胞聚集指数、血细胞比容,(t=2.59,P<0.05,t=3.48.P<0.05,t=2.29,P<0.05),TCD的平均速度、频谱、频窗明显改善。结论灯盏花可降低血粘度、活血化瘀、扩张血管、改善脑微循环及脑供血,其疗效明显优于丹参注射液,是防治缺血性脑血管病较理想的药物。
Objective To observe the effect of Breviscapine injection on the hemorheology and transcranial Doppler (TCD) in ischemic cerebrovascular disease. Methods Ninety patients with ischemic cerebrovascular disease were randomly divided into two groups, 45 cases were treated with 40ml Erigeron injection in a liquid 250ml intravenous drip once a day for 20 days for one course of treatment; 45 cases were treated with compound salvia miltiorrhiza injection Control. Observe the improvement of hemorrheology and TCD after the treatment of Breviscapus. Results Erigeron can significantly reduce plasma viscosity, erythrocyte aggregation index, hematocrit (t = 2.59, P <0.05, t = 3.48.P <0.05, t = 2.29, P < 0.05), TCD average speed, spectrum, frequency window significantly improved. Conclusion Erigeron can reduce blood viscosity, promote blood circulation and blood circulation, dilate blood vessels, improve brain microcirculation and cerebral blood supply, and its curative effect is better than that of Salvia miltiorrhiza injection. It is an ideal drug for preventing and curing ischemic cerebrovascular disease.