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近年来有人多次提出，与年龄有关的维生素Ｄ内分泌系统的变化可能与骨丢失和骨质疏松症有关。本文对１０８名４５～８５岁冈比亚妇女维生素Ｄ水平与骨矿含量（ＢＭＣ）关系进行了研究。研究对象选自于一项钙与骨代谢的课题。除维生素Ｄ水平与ＢＭＣ的关系，对维生素Ｄ与肌肉强度，膳食钙对ＢＭＣ的影响也做了探讨。结果表明：（１）与其他同类人群比较，冈比亚妇女血浆２５（ＯＨ）Ｄ的水平较高，但随着年龄的增长及季节的变冷（１２月～２月）而降低。（２）前臂，手腕及腰椎ＢＭＣ随着年龄的增长而下降。（３）没有发现维生素Ｄ水平与ＢＭＣ或肌肉强度有关，这种无关性不受骨与身体大小及血样采取季节的影响。（４）冈比亚妇女食用富含钙食物频率很低；叶菜类食用量可能与手腕部ＢＭＣ减少有关。这样，在冈比亚人群中，本次研究不能证明维生素Ｄ在与年龄有关的骨丢失中起重要作用。
In recent years, it has been repeatedly suggested that the age-related changes of vitamin D endocrine system may be related to bone loss and osteoporosis. This article studied the relationship between vitamin D levels and bone mineral content (BMC) in 108 Gambian women aged 45-85 years. The subjects were selected from a topic of calcium and bone metabolism. In addition to the relationship between vitamin D levels and BMC, the effects of vitamin D and muscle strength, dietary calcium on BMC were also explored. The results showed that: (1) Compared with other similar groups, the level of plasma 25 (OH) D in Gambian women was higher, but decreased with age and seasonal cooling (December to February). (2) forearm, wrist and lumbar BMC decreased with age. (3) No correlation was found between vitamin D levels and BMC or muscle strength. This independence was not affected by the bone and body size and the seasonal effects of blood samples. (4) Gambian women have a low frequency of calcium-rich foods; leafy food intake may be related to a reduction in BMC at the wrist. Thus, in the Gambian population, this study does not prove that vitamin D plays an important role in age-related bone loss.