5DFRXXL region of long myosin light chain kinase causes F-actin bundle formation

• 作 者: YANG Chunxiang WEI Dongmei CHE
• 机 构: ModelAnimalResearchCenter,MedicalCollege,NanjingNormalUniversity
• 出 处: 中国科学通报：英文版
• 发表日期: 2005年18期
• 关键词: 肌浆球蛋白链 致活酶 肌丝 DFRXXL 生物学 myosin light chain kinase myofilament actin bundle p
• 基金项目: 国家自然科学基金，国家科技攻关项目

Long myosin light chain kinase (L-MLCK) contains five DFRXXL motifs with ability to bind F-actin. Binding stoichiometry data indicated that each DFRXXL motif might bind each G-actin, but its biological significance remained unknown. We hypothesized that L