Graves病患者血甲状旁腺激素、钙、磷、碱性磷酸酶基础值的观察

• 作 者: 史京衡 吴增常 滕小洪 宋锦芬 沈希康
• 机 构: 上海铁路局中心医院内科,上海铁路局中心医院内科,上海铁路局中心医院内科,上海铁路局中心医院内科,上海铁路局中心医院内科 上海 200072,上海 200072,上海 200072,上海 200072,
• 出 处: 铁道医学
• 发表日期: 1990年04期
• 关键词: 甲状旁腺激素 Graves病 碱性磷酸酶 血磷 突眼性 平衡调节 正常人血浆 负相关 成骨细胞 骨吸收

对照观察了28例Graves病患者及29名正常人血浆甲状旁腺激素、(PTH)血钙、血磷、碱性磷酸酶的基础值。Graves病组血碱性磷酸酶明显高于对照组,而PTH、钙、磷无显著差异。Graves病组血钙>2.75mmol/L者占21%,与某些文献大致相符。正常组血钙与PTH基础值间呈负相关,而Graves病组该两值间无相关,提示Graves病时血钙浓度的平衡调节中PTH以外的因素如甲状腺激素等可能对其影响较大。

The baseline values ​​of serum PTH, serum calcium, phosphorus and alkaline phosphatase in 28 patients with Graves disease and 29 normal controls were observed. Graves disease serum ALP was significantly higher than the control group, while PTH, calcium, phosphorus no significant difference. Graves disease serum calcium> 2.75mmol / L accounted for 21%, in line with some literature roughly. The normal group of serum calcium and PTH was negatively correlated, while there was no correlation between the two values ​​of Graves ’disease, suggesting that factors other than PTH in the regulation of serum calcium concentration during Graves’ disease may be greatly influenced by thyroid hormones.