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本文报道了服氟乙酰胺小鼠体内血吸虫基本生化成分的变化及虫体柠檬酸积聚与虫肝移的关系。测定结果表明,血吸虫肝移与其体内柠檬酸积聚量有关。体外试验表明,血吸虫乳酸生成量与其葡萄糖利用量之比,在给药2次后从1下降至0.65左右,表明此时虫体糖酵解亦已发生故障,此外,对有氧代谢在血吸虫代谢中的重要性也进行了讨论。
This article reports the changes of the basic biochemical composition of Schistosoma japonicum in mice treated with fluoroacetamide and the relationship between citric acid accumulation and insect pests and liver metastasis. The results show that schistosome liver transplantation and its accumulation of citric acid in vivo. In vitro tests showed that the ratio of lactate production to glucose utilization of Schistosoma japonicum decreased from 1 to 0.65 after 2 administration, indicating that the glycolysis of the parasites had also failed at this time. In addition, The importance of also discussed.