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目的:探讨中西医结合疗法治疗中晚期胃癌穿孔的临床疗效。方法:本文对收治的中晚期胃癌穿孔采用中西医结合疗法治疗,比较两组患者的近期疗效、生活质量、体重指数及不良反应发生情况。结果:治疗结束后对比两组的治疗效果显示,研究组CR10例,PR 19例,SD 16例;PD 10例,总缓解率(CR+PR)为52.73%,与对照组相比近期疗效无明显差异(P>0.05)。研究组中生活质量提高23例,稳定16例,降低16例,与对照组相比,研究组的生活质量明显提高,且差异具有统计学意义(χ2=20.15,P<0.05)。与对照组相比,研究组的体重指数变化有明显差异,且差异具有统计学意义(χ2=24.99,P<0.05)。研究组的不良反应发生率明显低于对照组,且差异具有统计学意义(χ2=9.74、4.79、4.79、15.71、8.18、14.70、4.58,P<0.05)。结论:中西医结合治疗中晚期胃癌穿孔具有良好的近期疗效,而且在改善生活质量、增加体重、减轻不良反应等方面明显优于对照组。
Objective: To investigate the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of perforation of advanced gastric cancer. Methods: In this paper, the treatment of advanced gastric cancer perforation treated by Integrative Medicine, the two groups of patients with short-term efficacy, quality of life, body mass index and adverse reactions. Results: Compared with the control group, the treatment effect of the two groups showed that there were 10 cases in the study group, 19 cases in the PR group and 16 cases in the SD group, and 10 cases in the PD group had a total response rate (CR + PR) of 52.73% Significant difference (P> 0.05). The quality of life in the study group increased 23 cases, 16 cases were stable and 16 cases lower. Compared with the control group, the quality of life in study group increased significantly (χ2 = 20.15, P <0.05). Compared with the control group, the research group had significant differences in body mass index, and the difference was statistically significant (χ2 = 24.99, P <0.05). The incidence of adverse reactions in the study group was significantly lower than that in the control group (χ2 = 9.74,4.79,4.79,15.71,8.18,14.70,4.58, P <0.05). Conclusion: Integrative Chinese and Western medicine treatment of advanced gastric cancer perforation has a good short-term efficacy, but also in improving quality of life, increase weight, reduce adverse reactions was significantly better than the control group.