无低氧血症稳定期老年轻中度慢性阻塞性肺疾病患者左室肥大的相关研究

• 作 者: 张剑青 刘凌 方利洲 赵芝焕 戴路明
• 机 构: 昆明医科大学第一附属医院呼吸科,
• 出 处: 中国实用内科杂志
• 发表日期: 2015年03期
• 关键词: 老年轻 左室质量 肺过度膨胀 低氧血症 左心收缩功能 右心功能衰竭 吸气分数 呼吸系统并发症 稳定期 肺动脉高压

慢性阻塞性肺疾病(简称慢阻肺)的病死率已上升至世界第4位,其死亡原因除与呼吸系统并发症直接相关外,还与心血管系统合并症密切相关[1]。慢阻肺可导致肺动脉高压和右室增大从而发生右心功能衰竭,同时还经常合并左心收缩功能障碍。亦有报道慢阻肺患者存在左心室舒张功能障碍[2],但绝大多数报道均为在重度和极重度慢阻肺患者中(GOLD指南中3~4级)已出现缺氧和右心增大者,

The mortality of chronic obstructive pulmonary disease (COPD) has risen to No. 4 in the world. The cause of death is not only directly related to respiratory complications, but also closely related to cardiovascular complications [1]. Chronic obstructive pulmonary disease can lead to pulmonary hypertension and right ventricular enlargement to the occurrence of right heart failure, often also combined with left ventricular systolic dysfunction. It has also been reported that COPD patients have left ventricular diastolic dysfunction [2], but the vast majority have reported hypoxia and right ventricular dysfunction in patients with severe and severely COPD (grades 3-4 in the GOLD guidelines) Increase,