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目的 探讨不同类型弱视儿童治疗前后图形诱发电位的变化.方法 弱视儿童86例137眼,按弱视类型分为斜视性弱视组、屈光参差性弱视和屈光不正性弱视组;正常对照25例50眼.弱视治疗前后行图形诱发电位(pattern visual evoked potential,PVEP)检查并分析治疗前后的变化.结果 弱视组较正常对照组PVEP P100潜伏期延长,振幅降低(P<0.05),各弱视组P100潜伏期存在差异.弱视治疗后,各弱视组视力提高,P100潜伏期缩短,振幅增高,屈光不正性弱视疗效优于斜视性弱视及屈光参差性弱视.结论 弱视治疗后,患儿视力提高,PVEP可作为弱视患者诊断、治疗及随访的客观指标.“,”Objective To investigate the changes of pattern visual evoked potential before and after the treatment of different kinds of amblyopia.Methods 86 patients (137 eyes) with amblyopia were divided into three groups: strabismic amblyopia group, anisometropic amblyopia group, ametropic amblyopia group and with normal control group (25 patients, 50eyes). The pattern visual evoked potentials and visual acuity were recorded before and after amblyopia treatment.Results Compared with normal control group, the latency of wave P100 prolonged, and the amplitude reduced (P<0.05)in amblyopia patients. There were difference of the latency of wave P100 among strabismic amblyopia group, anisometropic amblyopia group, ametropic amblyopia group. The visual acuity improved, the latency of wave P100 shortened, and the amplitude increased after treatment. The curative efifcacy of ametropic amblyopia is superior to strabismic amblyopia and anisometropic amblyopia.Conclusions After the treatment of amblyopia,visual acuity of amblyopia patients was improved. PVEP can be used as amblyopia patients with diagnosis, treatment and follow-up objective indicators.