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基质金属蛋白酶(MMPs)是一类结构中含Zn2+和Ca2+的蛋白水解酶类,大量研究发现,MMPs在许多肿瘤组织中活性增强,与肿瘤的侵袭和转移及预后有关。1肿瘤的侵袭和转移肿瘤的侵袭和转移是肿瘤发生和演进过程中最危险的阶段。肿瘤侵袭和转移是一个主动过程,Littac[1]曾经把这一过程概
Matrix metalloproteinases (MMPs) are a class of proteolytic enzymes that contain Zn2 + and Ca2 +. A large number of studies have found that MMPs are highly active in many tumor tissues and are related to tumor invasion, metastasis and prognosis. Tumor Invasion and Metastasis Tumor invasion and metastasis are the most dangerous stages of tumorigenesis and evolution. Tumor invasion and metastasis is a proactive process that Littac [1] used to outline