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视网膜色素上皮(RPE)的功能类似一个泵,用以维持RPE与光感受器的紧密附着及视网膜下的干燥空隙。RPE又是防止从脉络膜毛细血管生理性渗漏的屏障。一些影响RPE的疾病,尤其是中心性浆液性视网膜病变(CSR),可以破坏这种屏障,使血浆从受损的RPE处渗漏至视网膜下间隙。CSR是RPE的自限性疾病。复发性CSR经过数年以后,后极部形成广泛的RPE退行性变,并造成视力障碍。CSR患者,在荧光造影
Retinal pigment epithelium (RPE) functions like a pump to maintain RPE-photoreceptor adhesion and dry sub-retinal space. RPE is again a barrier that prevents physiological leakage from the choriocapillaris. Some diseases that affect RPE, especially central serous retinopathy (CSR), can disrupt this barrier, allowing plasma to leak from the damaged RPE to the subretinal space. CSR is a self-limiting disease of RPE. Recurrent CSR After a few years, the posterior pole forms extensive RPE degeneration and causes visual impairment. CSR patients in fluoroscopy